Expression of programmed death ligand-1 (PDL-1) in Acute Myeloid Leukemia Patients and its relation to post induction

South Egypt Cancer Institute

Assiut University

Expression of programmed death ligand-1 (PDL-1) in Acute Myeloid Leukemia Patients and its relation to post induction

Research Authors
LA Abdel Hafeez, SG Mansor, AM Zahran, HB Hamed, MR Abdel Hameed, RM Bakry
Research Member
Lamyaa Ahmed Abdelhafeez Ahmed
Research Department
Department of Clinical Pathology
Research Year
2021
Research Journal
SECI Oncology
Research Abstract

Background and aim: In spite of approval of new therapeutic modalities, the clinical outcome of patients with acute myeloid leukemia (AML) remains unsatisfactory. Accurate risk stratification of patients is crucial for improving their outcome. Programmed death receptor-ligand 1 (PD-L1) plays an important role in the progression of malignant disorders. So we aimed to analyze PD-L1 expression on AML cells by flow cytometry and its relation to post induction response.