In-place analysis for offshore platforms is essentially required to ensure the structural integrity of platform components under extreme environmental conditions. The pile soil interaction is of great concern in structural behaviour of jacket-type fixed offshore platforms. Numerical modelling of a case-study platform with soil-pile-jacket-structure interaction is developed, the pile response demands in terms of lateral displacement and maximum bending moment and shear force, as well as soil reaction are investigated. The topsoil layers have important effects on the responses of the platform and supporting piles. A decrease in the upper soil layers’ resistance leads to higher lateral displacement responses at platform base and a decrease in the shear force and bending moment along the pile shaft. The response results of the soil-structure interaction model of the jacket foundation, confirm that the flexible foundation model simulation is necessary to estimate the loads and response demands of the offshore platform well.