Primary Sjӧgren's Syndrome with Granulomatous Interstitial Nephritis

Faculty of Medicine

Assiut University

Primary Sjӧgren's Syndrome with Granulomatous Interstitial Nephritis

Research Authors
Walaa H. Mohamad, Ahmad B. Elden, Wessam Ismail, Mahmoud Abd El-Radi
Research Department
Internal Medicine
Research Journal
Journal of Medical Science and Clinical Research
Research Member
Ahmed Bahi-Eldeen Ahmed Abdel-Rahim
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2015
Research_Pages
8016-8020
Research Abstract

Abstract
Sjӧgren's syndrome (SS) is a systemic autoimmune disease affecting mainly the exocrine glands. Tubulointerstitial
nephritis (TIN) is the most predominant renal involvement with lymphocyte and plasma cells
infiltration of the interstitium. We report a case of young female with SSpresented withrenal tubular
acidosis (RTA), polyradiculoneuropathy &proteinuria. Renal biopsy revealed granulomatous interstitial
nephritis. Granuloma formation is rarely seen in cases of SS.
Key Words:Sjӧgren's syndrome, Granulomatous tubulo-interstitial nephritis