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Trichloroacetic Acid With Microneedling Versus Trichloroacetic Acid Alone for Treating Melasma

Research Authors
Eman R Hofny, Amira A Abdel-Motaleb, Safaa Ahmed Hamed, Howida Omar Twisy
Research Date
Research Publisher
LWW
Research Vol
49
Research Year
2023
Research_Pages
66-71
Research Abstract

Abstract

BACKGROUND 

Melasma is a common acquired disorder of hyperpigmentation which is difficult to treat.

OBJECTIVE 

We aim to evaluate the efficacy and safety of combined microneedling with trichloroacetic acid in the treatment of melasma.

PATIENTS AND METHODS 

Forty women with facial melasma were included and randomly classified into 2 groups. Group A included 20 patients treated with bimonthly session of trichloroacetic acid 25% peeling (8 sessions) combined with a monthly session of microneedling (4 sessions). Group B included the other 20 patients that were treated by bimonthly trichloroacetic acid 25% peeling session (8 sessions) alone.

RESULTS 

After 1 and 3 months of treatment, the mean melasma area and severity index, modified melasma area and severity index, and melasma severity index scores showed significant improvement in each group (p < .05 for each). At 1 and 3 months, the mean percentages of change of all scores were significantly higher in group A than group B (p < .05).

CONCLUSION 

Combined trichloroacetic acid peel with microneedling is effective and a safe option for treating melasma.