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A New Isoflavone from Blepharis ciliaris of an Egyptian Origin

مؤلف البحث
Mohamed A. El-Shanawany, Hanaa M. Sayed, Sabrin R. M. Ibrahim, Marwa A. A. Fayed, Mohamed M. Radwan, Samir A. Ross
قسم البحث
مجلة البحث
Med. Chem. Res., DOI 10.1007/s00044-012-0228-2
تصنيف البحث
1
عدد البحث
Vol. 22
سنة البحث
2013
المشارك في البحث
ملخص البحث

A phytochemical study of the aerial parts of Blepharis ciliaris (L.) B.L. Burtt. led to the isolation of one new isoflavone glycoside caffeic acid ester: genistein-7-O-(6"-O-E-caffeoyl--D-glucopyranoside) (4), along with seven known compounds: methyl veratrate (1), methyl vanillate (2), protocatechuic acid (3), naringenin-7-O-(3"-acetyl-6"-E-p-coumaroyl--D-glucopyranoside) (5), naringenin-7-O-(6"-E-p-coumaroyl--D-glucopyranoside) (6), apigenin-7-O-(6"-E-p-coumaroyl--D-glucopyranoside) (7), and acteoside (8). Their structures were established on the basis of detailed analyses of physical, chemical, and spectral data. Compounds 1, 2, 3, 6, and 8 were isolated for the first time from this plant. The antioxidant activity of the different extracts as well as for some of the isolated compounds was evaluated.