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Zeaoxazolinone, a New Antifungal Agent from Zea mays Roots

Research Authors
Gamal A. Mohamed, Sabrin R.M. Ibrahim, Mohamed S.A. Abdelkader, Nawal M. Al-Musayeib, Mohamed Ghoneim, Samir A. Ross
Research Department
Research Journal
Med. Chem. Res., DOI: 10.1007/s00044-014-1026-9
Research Rank
1
Research Vol
Vol. 23
Research Year
2014
Research Abstract

A new 7-methoxy-2-benzoxazolinone dimer named zeaoxazolinone (2), together with four known compounds; 9-Z-hexadecenoic acid (1), 6-methoxy-benzoxazolinone (3), gallic acid (4), and -sitosterol-3-O--D-glucopyranoside (5) were isolated from Zea mays L. roots. The structural elucidation of isolatedmetabolites was established on the basis of UV, IR, 1D, 2D NMR, and MS spectral analyses. Compound 2 exhibited a potent antifungal activity against Aspergillus flavus, Fusarium oxysporum, and Candida albicans.