Research Department
Research Journal
Pak J Pharm Sci
Research Publisher
NULL
Research Rank
1
Research Vol
Vol.28, No.2
Research Website
http://www.pjps.pk/wp-content/uploads/pdfs/28/2/Supplementary/15-SUP-243.pdf
Research Year
2015
Research Member
Research Abstract
Abstract: A novel β-lactam derivative, albactam, was isolated from the alcoholic extract of the flowers of Albizia
lebbeck. It showed a significant anti-aggregatory activity against adenosine diphosphate and arachidonic acid induced
guinea-pigs’ platelets aggregation in vitro. Six more known compounds were also isolated and fully characterized by
measuring 1D and 2D NMR, two of them are the triterpenes β- amyrin and 11α, 12α-oxidotaraxerol, two ceramide
derivatives and two flavonoids, kampferol 3-O-rutinoside and rutin.