Research Date
Research Department
Research Journal
Current drug metabolism
Research Publisher
Bentham Science Publishers
Research Rank
Q2
Research Vol
21
Research Website
https://doi.org/10.2174/1389200221666200502015203
Research Year
2020
Research Member
Research_Pages
235-244
Research Abstract
p75ECD-Fc is a recombinant human protein that has recently been developed as a novel therapy for Alzheimer’s disease. Current studies showed that it is able to alleviate Alzheimer’s disease pathologies in animal models of dementia. Thus, knowledge about the pharmacokinetic behavior and tissue distribution of this novel protein is crucial in order to better understand its pharmacodynamics and more importantly for its clinical development.