Synthesis of a New Diels-Alder Quinone Adduct and Its Use in Preparing Thiazolo- and Oxazoloquinolines

Faculty Of Science

Assiut University

Synthesis of a New Diels-Alder Quinone Adduct and Its Use
in Preparing Thiazolo- and Oxazoloquinolines

Research Authors
A. S. Hammam, M. S. K. Youssef,* Sh. M. Radwan, and M. A. Abdel-Rahman
Research Abstract

Syn (or anti) cinnamaldehydeoxime (1a, b) undergoes Diels-Alder addition to tetrabromo-p-benzoquinone (2)
in dry xylene in 1 : 1 and 2 : 1 molar ratios to give the mono- and diadducts 3 and 4a, b respectively. The
reaction of 3 with thioamides in ethanol gave thiazoloquinoline diones 6a-d, whereas with acid amides in ethylene glycol, it gave oxazoloquinolinediones 12a-f.

Research Department
Department of chemistry
Research Journal
Bull. Korean Chem. Soc. ,
Research Member
Mona Ahmed Abdel Rahman Ali
Research Publisher
NULL
Research Rank
1
Research Vol
25(6),
Research Website
NULL
Research Year
2004
Research Pages
, 779-785