Tungsten oxide semiconductor (WO₃) modified using transition metals (Ni, Fe, and Zn) was synthesized via microwave-assisted solution combustion method. Ni, Fe, and Zn were doped in the WO₃ structure to improve the photocatalytic efficiency. The prepared powders were characterized by X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray spectroscopy analysis to investigate products' structural and morphological properties and surface composition. The materials show a monoclinic structure of WO₃ with small shifts in the peak position for each catalyst. Reactive blue 194 (RB 194) aquatic solution was used for photodegradation experiments under UV irradiation to evaluate the photocatalytic properties. The results showed an improvement in photocatalytic activity of host structure within doping the iron and nickel, whereas adding zinc made a decline in decolorization efficiency of WO₃. The photocatalytic performance of samples is in the order of WO₃:Ni > WO₃:Fe > WO₃ > WO₃:Zn. The influences of operational parameters were evaluated for each catalyst to obtain the optimum conditions of the photocatalytic reaction.