Cotton is a cash crop and its raw material is extremely important for use in textile industry. Pakistan comes in top exporter of cotton. Cotton crop is under different stresses during its production out of which pest pressure is most important to deal with. Rural Education & Economic Development Society (REEDS) Pakistan is working for production of better of cotton along with promotion of less pesticide use thus mitigating the environmental pollution. REEDS has established field study for use of neem extract as botanical spray against sucking pests and diseases. This experiment was done on farmer fields of Vehari and Rahim Yar Khan, Punjab and Dadu, Sindh. Botanical spray was used against sucking pests to delay the application of first pesticide for maximum number days. Which would ultimately reduce the number of pesticides applied along with less residual effects on humans and environment. The pest scouting data of trial plot clearly show the decrease in pest population after application of neem extract up to 79 days after sowing in comparison to control plot. Similarly, number of total pesticides used in trail plots were less in comparison to control plots.