We conducted a retrospective analysis to investigate the clinical outcome of combined-modality therapy using multiagent chemotherapy and involved-field radiotherapy in treatment of children with Hodgkin's lymphoma. Fifty eight cases with newly diagnosed Hodgkin's lymphoma were analyzed. The median follow-up duration was 46 months (range 3–72 months). The 4-year overall and event-free survival rates were 91.5% and 69.7% respectively. High-risk disease (stage IIIB and IV), presence of B symptoms, lymphocyte depletion subtype, bulky disease and late response to chemotherapy were poor prognostic factors. Stage-adapted combined-modality therapy resulted in satisfactory outcome in treatment of pediatric Hodgkin's lymphoma.
المشارك في البحث
قسم البحث
سنة البحث
2010
مجلة البحث
Leukemia Research
الناشر
NULL
عدد البحث
Vol. 34, Issue 11
تصنيف البحث
1
صفحات البحث
PP. 1447-1452
موقع البحث
NULL
ملخص البحث