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Computed tomography perfusion as a predictor of gastric cancer grades

مؤلف البحث
Lamiaa MR Khalaf, Mostafa AM El-sharkawy, Marwa Samy, Emad Saad, Salah Khallaf, Hagar HM Desoky, Mohamed M El-Barody, Hosam M Kamel
المشارك في البحث
قسم البحث
تاريخ البحث
سنة البحث
2024
مجلة البحث
Egyptian Journal of Radiology and Nuclear Medicine
الناشر
Springer Berlin Heidelberg
عدد البحث
Volume 55, Issue 1
صفحات البحث
202
موقع البحث
https://scholar.google.com/scholar?oi=bibs&cluster=6031544444250432461&btnI=1&hl=en
ملخص البحث

Gastric cancer stands as one of the most prevalent malignancies globally, conventional endoscopic specimens have been the primary means of diagnosing preoperative gastric histopathology, however, their limitations in capturing intra-tumor heterogeneity compromise their efficacy in evaluating angiogenesis. Perfusion Computed Tomography (P-CT) emerges as a pivotal functional imaging modality, facilitating objective assessment of tissue perfusion, serving as a marker of angiogenesis. So, our research objective was to evaluate the efficacy of CT perfusion imaging in the prediction of histological grades of gastric tumors using quantitative perfusion parameters such as permeability surface (PS), blood flow (BF), mean transient time (MTT), and blood volume (BV), in addition to the qualitative scoring system then comparing the findings with the histopathological results.