ABSTRACT

Aim: This study was performed to examine the anti-microbial effect of different percentages of titanium dioxide and chitosan nanoparticles to heat cured poly methyl meth acrylate.

Subjects and methods: 120 specimens of heat cure acrylic resin were grouped according to nano additives concentrations for testing anti-microbial effect.

Results: the addition of chitosan nano particles to PMMA in 0.3% and 0.5% decreased the microbial biofilm formation in comparison to the control (PMMA without chitosan). the addition of Tio2 nano particles in concentrations 1% and 2% decreased the microbial biofilm formation more than the chitosan nano particles concentrations 0.3 and 0.5.

Conclusion: The addition of chitosan nano particles to PMMA in 0.3% and 0.5% decreased the microbial biofilm formation in comparison to the control (PMMA without chitosan). the addition of Tio2 nano particles in concentrations 1% and 2% decreased the microbial biofilm formation more than the chitosan nano particles. The higher concentrations of the chitosan and Tio2 nano particles resulted in stronger antimicrobial effect.