Abstract Objective: This study was performed to evaluate the feasibility and safety of early sheath
removal after percutaneous coronary intervention (PCI) using a locally designed Assiut Femoral
Compression Device (AFCD2) vs. manual compression (MC).
Background: Due to antithrombotic therapy before, during, and after PCI, the arterial femoral
sheath is generally not removed early after PCI.
Patients and methods: This was a randomized, controlled trial. We enrolled all patients undergoing
PCI at Assiut University Hospitals from September, 2013 to December, 2013. At the end of PCI,
the arterial hemostasis method was randomly assigned 1:1 to AFCD2 vs. MC. The sheaths were
removed 2 h after PCI, instead of conventional 6 h, in the AFCD2 arm.
Results: The trial assigned 100 patients (mean age 57± 9 years, 75% men) to AFCD2 (n= 50) vs.
MC (n= 50). Both groups were comparable regarding baseline characteristics. Concerning the primary
effectiveness end point, there was significantly shorter mean time-to-ambulation with AFCD2
(8.2 ± 1.42 h) vs. MC (12.02± 0.22 h; p= <0.001). This was directly reflected on shorter time for
hospital discharge eligibility in AFCD2 (11 ±1 h) vs. MC (15 ±1 h; p= <0.001). As regards
safety, none of our research population experienced major adverse events. The use of AFCD2
was associated with similar occurrence of minor complications, mainly ecchymosis and oozing,
compared with MC.
Research Member
Research Year
2015
Research Journal
The Egyptian Heart Journal
Research Publisher
NULL
Research Vol
42-3
Research Rank
1
Research_Pages
69–77
Research Website
NULL
Research Abstract