Background: Acne vulgaris is a very common disease in adolescence and adulthood. Acne has negative social, psychological and physical impact on patients. There are many modalities for treating acne vulgaris. Aim of the work: This work aims to evaluate the efficacy of intense pulse light (IPL) in treatment of facial acne vulgaris in comparison with medical treatment. Materials and Methods: Twenty three patients were included in this work. They were selected from acne patients attended the department of Dermatology and Androlgy, Qena university Hospital, South Valley university from June 2009 to January 2010. Patients were divided into two groups, 1st (12 patients) treated with IPL and 2nd (11 patients) treated with medical treatment.