Objective: Congenital and acquired prothrombotic disorders have been highlighted in a
recent series of cerebrovascular stroke (CVS), with a controversial role in pathogenesis. The
aim is to study some prothrombotic risk factors [activated protein C (APC) resistance, von
Willebrand factor (vWF), anticardiolpin (ACL) antibodies and plasma homocysteine] in
children with ischemic stroke, and to evaluate the role of aspirin and low molecular weight
heparin (LMWH) in its management in relation to outcome. Methods: A total of 37 cases