There are several cancers and diseases which affect the pericardial space around
the heart, and pericardial mesothelioma is one of the rarest pathology. It is the most common
primary malignant pericardial tumor. The clinical presentation of malignant pericardial
mesothelioma includes chest pain, shortness of breath, coughing and severe nocturnal
sweating. In this article, we report the fifth case of the localized isolated pericardial
mesothelioma in the literature and the longest survival at two years reported so far