Abstract: Background and purpose: The safety of bare platinum coils has
been widely described in the literature. This study aimed to report the
first series of intracranial aneurysms treated with Barricade bare
platinum coils with a comprehensive evaluation of their procedural safety
and post-procedural anatomical results.
Methods: Patients with intracranial aneurysms treated between October
2013 and December 2015 by simple coiling or balloon-assisted coiling with
Barricade Coils (Blockade Medical, Irvine, California, USA) were
prospectively included in a database and retrospectively studied. For all
included patients, the patient and aneurysm characteristics, procedural
complications, technical issues, post-operative anatomical results, and
one-month clinical outcome (modified Rankin Scale) were evaluated by an
independent interventional neuroradiologist.
Results: 88 patients harboring 97 aneurysms were included. Procedural
complications and technical issues were encountered in 17 and 5 patients
(19.3 and 5.7%, respectively) but clinical worsening in only 2 patients
(2.2%). There was no treatment-related mortality. After one month,
morbidity (mRS≥1) was observed in 19 patients (21.8%), 17 related to
subarachnoid hemorrhage (SAH) in patients with ruptured aneurysms (19.4%)
and 2 related to thromboembolic events in patients with unruptured
aneurysms (2.3%). Nine patients initially presenting with a ruptured
aneurysm were deceased at 1 month as a consequence of SAH (10.2%).
Adequate occlusion was observed post-operatively in 94.8% of the
aneurysms (complete occlusion in 81.4% and residual neck in 13.4%).
Conclusion: Endovascular treatment of intracranial aneurysms with
Barricade coils is feasible and the demonstrated overall safety results
are within the ranges found in the literature for other coils. Immediate
anatomical results are satisfying.