Background: Cryptosporidium parvum is an obligate intracellular parasite of the
Coccidia class that infects the microvilli epithelial cells of the digestive and respiratory
systems Objectives: this study aims to detection of the prevalence of cryptosporidiosis
among immune compromised children who receive chemotherapy and to compare the
three different methods for diagnosis of Cryptosporidium Methodology: 200 children in
Aswan oncology institute were enrolled in this study, clinical assessment as well as stool
examination by modified Ziehl-Neelsen stain, ELISA assay and Immunofluorescence
tests were done. Results: The study showed that the over-all infection was 43.5% by
immunofluorescence method, 40.5% by ELISA and 28% by modified Ziehl -Neelsen stain.
Infection rate increases in haematological malignancies (AML54.8%, HD46.2 %,
ALL41.6%, NON HD 27.3%) than non haematological malignancy (wilms 50%,
sarcoma 45.5%, and neuroblastoma 42.9%). Conclusion: Cryptosporidium infection is
an important public health problem in Immunocompromised children, raising awareness
about cryptosporidiosis has very important effect to decrease prevalence of this parasitic
infection.
قسم البحث
مجلة البحث
Egyptian Journal of Medical Microbiology
المشارك في البحث
الناشر
www.ejmm-eg.com info@ejmm-eg.com
تصنيف البحث
1
عدد البحث
Volume 27 / No.2 / April 2018
موقع البحث
www.ejmm-eg.com info@ejmm-eg.com
سنة البحث
2018
صفحات البحث
143-149
ملخص البحث