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ASSESSMENT OF THE EFFECT OF ALLIUM SATIVUM(GARLIC) AND CURCUMA LONGA(CURCUMIN) IN COMBINATION WITH DRUGS ON CULTURED TRICHOMONAS VAGINALIS

مؤلف البحث
AHMED K. DYAB , HANY A. FAROUK ,MOHAMMED F. MOHAMMED AND YASSER M. MOHAMED
تاريخ البحث
مجلة البحث
Journal of the Egyptian Society of Parasitology
المشارك في البحث
الناشر
the Egyptian Society of Parasitology
تصنيف البحث
international
عدد البحث
51 (1)
موقع البحث
https://jesp.journals.ekb.eg.
سنة البحث
2021
صفحات البحث
23 - 28
ملخص البحث

Abstract
Trichomoniasis is an infectious disease caused by Trichomonas vaginalis. It inflicts severe complications to human genitourinary system. The devastating negative effects and resistance emerged to known medication impose the search for effective and safer alternatives. This study evaluated  the  effect  of curcumin  and  garlic as well as combination between their effective doses 
with Metronidazole
®
& Tinidazole
®
. So,  vaginal  swabs were  obtained  from the  symptomatic 
patients,  and  cultured  on modified Diamond's medium. Assessment  of  the herbs various concentrations at  different  follow-up  periods  was  done  by  counting dead T.  vaginalis trophozoites 
by using hemocytometer and trypan blue staining.The results showed that curcumin 400mg/ml 
gave a promising anti-Trichomonas especially when combined with garlic 90mg/ml that showed a 
high synergistic effec