Osteoprotegerin, Soluble Receptor Activator Nuclear Factor-κB Ligand, Nuclear Factor Kappa B and Intestinal Trefoil Factor 3 Are Promising Biomarkers In Diagnosis And Follow- up Inflammatory Bowel Disease Patients

كلية الطب

جامعة أسيوط

Osteoprotegerin, Soluble Receptor Activator Nuclear Factor-κB Ligand, Nuclear Factor Kappa B and Intestinal Trefoil Factor 3 Are Promising Biomarkers In Diagnosis And Follow- up Inflammatory Bowel Disease Patients

مؤلف البحث
Ragaa HM Salama , Mohammed A Medhat, Shimaa A Elghazally , Nesma G Farag, Aya A El Sanory ,Mohamed O Herdan, Tasneem A El Sanory , Amira A kamel .
تاريخ البحث
قسم البحث
قسم الكيمياء الحيوية
مجلة البحث
The Egyptian Journal of Hospital Medicine
المشارك في البحث
Nesma Gamal Abd Elnaem Farag
ملخص البحث

The hypothesis of this study based on OPG is the decoy receptor of sRANKL which bind with its receptor RANK and activate NF-κB. This pathway may involve in the pathogenesis of IBD and any interference with pathway may affect the progress of the disease. The role of RANK/RANKL inhibition as an immunomodulatory.  While TFF3 is a good marker indicating healing of mucosa   and a state of remission.