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Early mobilisation in critically ill COVID-19 patients: a subanalysis of the ESICM-initiated UNITE-COVID observational study

مؤلف البحث
Philipp Kloss, Maximilian Lindholz, Annette Milnik, Elie Azoulay, Maurizio Cecconi, Giuseppe Citerio, Thomas De Corte, Frantisek Duska, Laura Galarza, Massimiliano Greco, Armand R. J. Girbes, Jozef Kesecioglu, Johannes Mellinghoff, Marlies Ostermann, Mari
تاريخ البحث
مجلة البحث
Annals of Intensive Care
المشارك في البحث
الناشر
Springer
عدد البحث
13
موقع البحث
https://doi.org/10.1186/s13613-023-01201-1
ملخص البحث

Background

Early mobilisation (EM) is an intervention that may improve the outcome of critically ill patients. There is limited data on EM in COVID-19 patients and its use during the first pandemic wave.

Methods

This is a pre-planned subanalysis of the ESICM UNITE-COVID, an international multicenter observational study involving critically ill COVID-19 patients in the ICU between February 15th and May 15th, 2020. We analysed variables associated with the initiation of EM (within 72 h of ICU admission) and explored the impact of EM on mortality, ICU and hospital length of stay, as well as discharge location. Statistical analyses were done using (generalised) linear mixed-effect models and ANOVAs.

Results

Mobilisation data from 4190 patients from 280 ICUs in 45 countries were analysed. 1114 (26.6%) of these patients received mobilisation within 72 h after ICU admission; 3076 (73.4%) did not. In our analysis of