Research Department
Research Journal
Diabetes/metabolism research and reviews
Research Member
Research Rank
1
Research Year
2015
Research Abstract
Background The study aimed to define the frequencies of type 1 diabetes-associated gene
polymorphisms and their associations with various diabetes-associated autoantibodies in
Egyptian children. Methods One hundred and one children with type 1 diabetes and 160
healthy controls from the same region were studied for HLA-DQB1, HLA-DQA1, and HLA-
DRB1 (DR4 subtypes) alleles; for INS and protein tyrosine phosphatase, non-receptor type
22 gene polymorphisms (rs689 and rs2476601); and for diabetes-associated