Bolus transit patterns in healthy subjects: a study using simultaneous im- pedance monitoring, videoesophagram, and esophageal manometry. Am J Physiol Gastrointest Liver Physiol 288: G1000–G1006, 2005; doi:10.1152/ajpgi.00372.2004.—Impedance monitoring (Imp) mea- sures bolus transit. Combining Imp with manometry (EM) allows the effect of contractile patterns on transit to be assessed. The objective of this study is to identify bolus transit patterns in normal subjects, correlate Imp findings with the gold standard barium esophagram (Ba), and compare bolus transit with concomitant EM findings. Simultaneous Ba-Imp-EM was performed for 2 min in 15 normal volunteers (women, 11; age, 43 yr). Combined impedance-pressure sites were 5, 10, 15, 20 cm above the lower esophageal sphincter (LES). Boluses (10 ml) of 45% barium mixed with 0.9% NaCl were swallowed at