Objective: The aim of our study is to assess the clinico-electrophysiological profile of
children with Guillain–Barré syndrome (GBS) in Upper Egypt and to compare the efficacy of
plasmapheresis versus other treatment modalities.
Patients and methods: This was a retrospective study of children from January 2010 to
October 2014 diagnosed as GBS. It included 62 cases.
Results: Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) was the
most prevalent type of GBS in our locality. As regards the treatment, 32 cases received
plasmapheresis while 30 patients received intravenous immunoglobulin. We found a
significant decrease in the duration of hospitalization and a significant increase in the number
of children with complete recovery in cases treated with plasmapheresis.
Conclusion: GBS is not uncommon in children of Upper Egypt, with AIDP the most prevalent
type. Plasmapheresis is the best treatment modalities for GBS as it reduces the duration of
hospital stay and hastens the recovery of those children.