Skip to main content

Low dose multidetector computed tomography in localizing thetransition zone of Hirschsprung’s Disease: A novel study

Research Authors
Gehan S. Seifeldeina,⇑, Nagham N. Omara, Nagla H. Abu Faddanb, Omar Abd Elraheem
Research Journal
The Egyptian Journal of Radiology and Nuclear Medicine
Research Member
Research Publisher
NULL
Research Rank
1
Research Vol
47
Research Website
: www.sciencedirect.com/locate/ejrnm
Research Year
2016
Research_Pages
1585–1590
Research Abstract

Objectives:The objectives of this study were the evaluation of low dose multidetector com-puted tomography (MDCT) in localizing the site of the transition zone (TZ) ofHirschsprung’s Disease (HD) for preoperative planning.Patients and methods:Twenty-two infants were recruited from pediatric and surgical clin-ics in Assiut University Hospital and Sohag University Hospital. The recruited patients weresedated before examination. Examinations were done using 64-rows MDCT. Each MDCTexamination was reviewed to determine the location and length of the TZ and comparedwith operative and pathological results. Results were analyzed by chi square test and inter-observer agreement using Kappa test.P< 0.05 was considered statistically significant.Results:According to operative and pathological data, the site of the TZ: 17 (77.27%) wereof short-segment disease (rectosigmoid HD), 2 (9%) were of long segment (above sigmoidcolon), and 3 (13.63%) were of ultrashort segment. A correct diagnosis of TZ by MDCT wasmade in 19 out of 22 with 82.4% sensitivity and 80% specificity. The site of TZ wasconcordant in 17. Results yielded a moderate strength of inter-observer agreement in local-izing the site of TZ (k= 0.546) and (P= 0.009).Conclusion:Low-dose MDCT has a good role in localizing the site of TZ of HD in infants.