Effects of oral ginkgo biloba extract on pregnancy complicated by asymmetrically intrauterine growth restriction: a double-blinded randomized placebo-controlled trial

Faculty of Medicine

Assiut University

Effects of oral ginkgo biloba extract on pregnancy complicated by asymmetrically intrauterine growth restriction: a double-blinded randomized placebo-controlled trial

Research Authors
Diaa Eldeen M. Abd El Aal, MD,1 Mohammed K. Ali, MD,1 Ahmed Y. Shahin, MD,1 Mahmoud S. Zakherah, MD,1 Mohamad S. Abdellah, MD,1 Ahmed F. Abdel-Kawi, MD,1 Mohamed S. Fahmy, MD2
Research Department
Department of Obstetrics and Gynecology
Research Journal
POG in Press
Research Member
Ahmed Yousef Hasanein Shahin
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
http://ir.uiowa.edu/pog_in_press/.
Research Year
2017
Research_Pages
11-
Research Abstract

NULLAbstract:

Objectives: to evaluate the effect of oral ginkgo biloba extract (GB)) on asymmetrical intrauterine growth restriction (IUGR).

Study Design: A randomized trial conducted at Assiut Women Health on 226 pregnant women with asymmetrical IUGR. The patients randomly received GB extract or placebo for 6 weeks. The main outcome measures were improvement in fetal weight and feto-maternal blood flow. The data were analyzed by Student’s t- test and chi- squared tests.

Result: There was a significant increase in the estimated fetal weight in the GB group (3047+ 127 gm) when compared to the placebo group (2734+ 127 gm) (p=<0.001). Moreover; there were significant increases in feto-maternal blood flow in GB group compared to the placebo group.

Conclusions: GB extract improves placental functions, Doppler indices and fetal weight in pregnancies complicated with IUGR fetuses.