No evidence of HEV genotype 1 infections harming the male reproductive system

Faculty of Medicine

Assiut University

No evidence of HEV genotype 1 infections harming the male
reproductive system

Research Authors
Mohamed A. El-Mokhtar a, Mohamed Ismail Seddik b, Asmaa O.B. Osman b, Amal A. Mahmoud b,
Sahar A. Mandour c, Eman Radwan d, Maha Ali d, Ali E Ismael e, Howida Omar Twisy f,
Haidi Karam-Allah Ramadan g, Rofaida Refaat Shehata f, Ibrahim M. Sayed
Research Department
Department of Clinical Pathology
Research Journal
Virology
Research Member
Amal Abdel-Aziz Mahmoud Abdel-Ghani
Research Publisher
Elsevier
Research Rank
1
Research Vol
Virology 554 (2021) 37–41
Research Website
www.elsevier.com/locate/virology
Research Year
2020
Research_Pages
37–41
Research Abstract

Extrahepatic disorders are recorded with hepatitis E virus (HEV) infection. The impact of HEV infection on the male reproductive system is a query. In this study, we retrospectively analyzed semen from infertile men and prospectively examined the semen from acute hepatitis E patients (AHE) for HEV markers. HEV RNA and HEV Ag were not detectable in the semen of infertile men nor the semen of AHE patients. Although HEV markers were
detectable in the urine of patients infected with HEV-1, these markers were absent in their semen. There is no significant difference in the level of reproductive hormones between AHE patients and healthy controls. Semen analysis of AHE patients did not show a notable abnormality and there was no significant difference in the semen quality and sperm characteristics between AHE and healthy controls.