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ASSESSMENT OF THE EFFECT OF ALLIUM SATIVUM(GARLIC) AND CURCUMA LONGA(CURCUMIN) IN COMBINATION WITH DRUGS ON CULTURED TRICHOMONAS VAGINALIS

Research Authors
AHMED K. DYAB , HANY A. FAROUK ,MOHAMMED F. MOHAMMED AND YASSER M. MOHAMED
Research Date
Research Department
Research Journal
Journal of the Egyptian Society of Parasitology
Research Member
Research Publisher
the Egyptian Society of Parasitology
Research Rank
international
Research Vol
51 (1)
Research Website
https://jesp.journals.ekb.eg.
Research Year
2021
Research_Pages
23 - 28
Research Abstract

Abstract
Trichomoniasis is an infectious disease caused by Trichomonas vaginalis. It inflicts severe complications to human genitourinary system. The devastating negative effects and resistance emerged to known medication impose the search for effective and safer alternatives. This study evaluated  the  effect  of curcumin  and  garlic as well as combination between their effective doses 
with Metronidazole
®
& Tinidazole
®
. So,  vaginal  swabs were  obtained  from the  symptomatic 
patients,  and  cultured  on modified Diamond's medium. Assessment  of  the herbs various concentrations at  different  follow-up  periods  was  done  by  counting dead T.  vaginalis trophozoites 
by using hemocytometer and trypan blue staining.The results showed that curcumin 400mg/ml 
gave a promising anti-Trichomonas especially when combined with garlic 90mg/ml that showed a 
high synergistic effec