Transepithelial photorefractive keratectomy: a prospective randomized comparative study between the two-step and the single-step techniques

Faculty of Medicine

Assiut University

Transepithelial photorefractive keratectomy: a prospective randomized comparative study between the two-step and the single-step techniques

Research Authors
Mahmoud Abdel-Radi, Mohamed Shehata, Magdi Mohammad Mostafa, Mohamed Omar M Aly
Research Date
Research Department
Department of Ophthalmology
Research Journal
Eye
Research Member
Mahmoud Abdelradi Abdelsalam
Mohamed Shehata Hussein Masoud
Magdi Mohammad Mostafa Hasan
Mohamed Omar Mohamed Ali
Research Publisher
Nature Publishing Group UK
Research Year
2023
Research Abstract

Objectives

To assess and compare the six-month outcome of the two-step transepithelial phototherapeutic keratectomy- photorefractive keratectomy (PTK-PRK) and the single-step transepithelial PRK for myopia and myopic astigmatism.

Methods

A prospective randomized study. The study enrolled 100 eyes of 50 patients with mild to moderate myopia or myopic astigmatism stratified into two groups, PTK-PRK (n = 50 eyes) and single step PRK (n = 50 eyes). Primary outcome measures were visual acuity and manifest refraction. Secondary outcome measures were epithelial healing duration, post-PRK pain scores and 3-month postoperative haze grading.

Results

Preoperative characteristics were similar in both groups (p value > 0.05). The mean uncorrected distance visual acuity (UDVA) at 1 week, 1 month, 3 and 6 months was significantly better in the single-step PRK group than in the two-step PTK-PRK group …