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Primary Sjӧgren's Syndromewith Granulomatous Interstitial Nephritis

Research Authors
Walaa H. Mohamad, Ahmad B. Elden, Wessam Ismail, Mahmoud Abd El-Radi
Research Date
Research Department
Research Journal
Journal of medical science and clinical research
Research Member
Research Abstract

Sjӧgren's syndrome (SS) is a systemic autoimmune disease affecting mainly the exocrine glands. Tubulointerstitial nephritis (TIN) is the most predominant renal involvement with lymphocyte and plasma cells
infiltration of the interstitium. We report a case of young female with SS presented with renal tubular acidosis (RTA), polyradiculoneuropathy &proteinuria. Renal biopsy revealed granulomatous interstitial nephritis. Granuloma formation is rarely seen in cases of SS.