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Predictors of nadir serum creatinine after drainage of bilaterally obstructed kidneys due to different etiologies

Research Authors
Rabea Ahmed Gadelkareem, Ahmed Mahmoud Abdelraouf, Ahmed Mohammed El-Taher, Abdelfattah Ibrahim Ahmed, Nasreldin Mohammed
Research Date
Research Department
Research Journal
International Urology and Nephrology
Research Publisher
Springer Netherlands
Research Year
2022
Research Abstract

Purpose

To identify the predictors of nadir serum creatinine (SCr) after drainage of bilaterally obstructed kidneys (BOKs) by different modes: double-J stent (JJ) versus percutaneous nephrostomy (PCN) and unilateral versus bilateral drainage.

Methods

A prospective non-randomized study was performed on patients with BOKs and raised SCr during December 2019–November 2021. Relevant variables were studied for improvement and non-improvement and for benign and malignant underlying obstructions (BUO and MUO).

Results

This study included 107 patients with BOKs including 68 (63.6%) males and 39 (36.4%) females. After drainage, 86 (80.4%) patients get improved, while 21 (19.6%) patients failed to reach a nadir SCr. Drainage by PCN was significantly higher in MUO, while JJ was significantly higher in BUO (p < 0.001). Also, bilateral drainage was a significant predictor of improvement in MUO (p …