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Role of diffusion magnetic resonance imaging (DWI) in laryngeal carcinoma

Research Authors
Mohammed Mahmoud Mohammed Roushdy1; Mahmoud Ragheb Elsherif2; Ezzat Mohamed Saleh Kayed2; Shimaa Farghaly3; Ahmed Ragab Sayed
Research Date
Research Journal
Egyptian Journal of Neck Surgery and Otorhinolaryngology
Research Member
Research Publisher
Egyptian Journal of Neck Surgery and Otorhinolaryngology
Research Year
2022
Research Abstract

Background and Purpose: To detect sensitivity and specificity of diffusion-weighted imaging (DWI) as a non-invasive technique in the detection of de-novo cases of cancer larynx
Patients and methods: Patients included in this research were patients suspected of de-novo cancer larynx; This study is a prospective randomized comparative clinical trial.
Results: The mean apparent diffusion coefficient (ADC) of laryngeal lesions (0.73± SD 0.23 x10-.3 mm2) was lower (p < 0.001) than the mean of the normal part of the larynx in the same patients (1.09± SD 0.099 x 10-.3 mm2), The cut-off value of the ADC using receiver operating characteristics was Conclusion: DWI is an easily reproducible and non-invasive technique that can accurately explore the larynx and became a very important diagnostic tool of laryngeal diseases. This study demonstrated the cut-off point of ADC value for discrimination of malignant lesion is <0.87x 10-.3 mm2/s with restricted diffusion in DWI images.