Abstract: Heart failure patients require complicated care that involves drugs controlling and extreme teaching about the significance of suitable nutrition, consistent exercise, symptoms control, and fluid checking. This study aimed to assess therapeutic compliance among old patients with cardiac failure in out patient’s clinic at Assiut City hospitals. Patients and methods: descriptive study design was conducted. The total sample size was 280 elderly patients who were selected by quota from 3 hospitals at Assiut City. Two tools, were used first, was interview questionnaire, second was heart failure compliance questionnaire scale. Results: it was found 59.3% of elderly patients were male, with mean age ± SD was 65.10 ± 6.12, 56.1% had poor knowledge scores, 66.8% were non-complaint with weight and 58.9% and 53.9% respectively of them were non-complaint with avoid drinking excessive fluid and keep a little salt food. Moreover, illustrated significant difference at all items of compliance with knowledge except compliance with take medication P= 0.305. Conclusion: More than half of studied elderly patient had poor knowledge score and this was correlate with non-therapeutic compliance among elderly patient. Recommendations: More studies should be implemented to assess therapeutic compliance, health education program for elderly about therapeutic compliance about heart failure.