Background: Chronic hepatitis is typically silent; signs and symptoms that present only in those with advanced
disease. The study aimed to: assess the quality of life and knowledge about the elderly patients with chronic
hepatitis at Assiut city. Patients and method: descriptive design was used in this study. It was conducted at two
Geriatric Homes, two Geriatric Social Clubs and Unit of Treatment for Viral Hepatitis. A convenient sample (300)
elderly participant divided into group 1 (150) and group 2 (150). Two tools were used: 1. Structure interview
questionnaire, 2. Chronic liver disease questionnaire. Results: It clarifies that 69.3% of group1 were males, versus
47.3% in group2. And 8.7% of the group1 has university, while 24.7% from group2. According to marital status
58.7% & 50.7% respectively of the group1 and group2 are married. And show negative correlations between a score
of knowledge with “Emotional Function” and “Worry”. The study concluded Negative correlation between the grade
of knowledge and quality of life domains in the group1. It recommends providing educational programs to improve
elderly knowledge about chronic hepatitis and early detection especially high risk group.