قسم البحث
مجلة البحث
Asian J. Chem.
تصنيف البحث
1
عدد البحث
Vol. 26, No. 23
موقع البحث
http://dx.doi.org/10.14233/ajchem.2014.17636
سنة البحث
2014
المشارك في البحث
ملخص البحث
Selective cytotoxic effect toward tumor cells but not the normal tissues represent a major challenge in cancer drug discovery. Herein, we describe the synthesis and selective antitumor activity of some HHT. All the synthesized compounds showed a good antitumor activity against leukemia K562 cells. In regard to cytotoxicity in normal cells, compounds (1-11) showed no cytotoxic effect within 200 μM range, however compounds 12-16 showed non-selective cytotoxic effect.