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Sagitol C, a new cytotoxic pyridoacridine alkaloid from
the sponge Oceanapia sp.

مؤلف البحث
Sabrin RM Ibrahim, Gamal A Mohamed, Ehab S Elkhayat, Mostafa A Fouad, Peter Proksch.
قسم البحث
مجلة البحث
Bulletin of Faculty of Pharmacy, Cairo University (2013) 51, 229–232
الناشر
Elsevier
تصنيف البحث
2
عدد البحث
51
موقع البحث
http://dx.doi.org/10.1016/j.bfopcu.2013.05.004
سنة البحث
2013
المشارك في البحث
ملخص البحث

A new pyridoacridine alkaloid named sagitol C (2) together with two known compounds; kuanoniamine C (1) and sagitol (3) were isolated from the EtOAc fraction of the Indonesian sponge Oceanapia sp. Their chemical structures were established on the basis of physical and
spectroscopic methods 1D and 2D NMR, in addition to mass spectrometry and comparison with
literature data. Sagitol C was found to exhibit cytotoxic activity when tested against different cancer
cell lines