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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
41 Design and Synthesis of Novel Isatin-Based derivatives Targeting Cell Cycle Checkpoint Pathways as Potential Anticancer Agents 2020
42 Novel 3-(Benzylidene)indolin-2-one Derivatives as Cyclin-Dependent Kinase (CDK) Inhibitors with Potential Anticancer Activity 2019
43 Novel 3-(Benzylidene)indolin-2-one Derivatives as Cyclin-Dependent Kinase (CDK) Inhibitors with Potential Anticancer Activity 2019
44 Novel 3-(Benzylidene)indolin-2-one Derivatives as Cyclin-Dependent Kinase (CDK) Inhibitors with Potential Anticancer Activity 2019
45 Novel 3-(Benzylidene)indolin-2-one Derivatives as Cyclin-Dependent Kinase (CDK) Inhibitors with Potential Anticancer Activity 2019
46 Novel indole-2,3-dione (isatin) derivatives as CDK2 inhibitors with potential anticancer activity. 2018
47 Novel indole-2,3-dione (isatin) derivatives as CDK2 inhibitors with potential anticancer activity. 2018
48 " Design, Synthesis and evaluation against Mycobacterium tuberculosis of azole piperazine derivatives as dicyclotyrosine(cYY)mimics" 2018
49 Pharmacokinetic studies of naproxen amides of some amino acid esters with promising colorectal cancer chemopreventive activity 2018
50 Utilization of microwave technology for simple, efficient and enhanced synthesis of spiro-thiazoldinediones with potential antimycobacterium activity. 2018