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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
101 Cu (I) Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition (CuAAC): Synthesis of 17α-[1-(Substituted Phenyl)-1,2,3-Triazol-4-yl]-19-Nortestosterone-17β-yl Acetates Targeting Progestational and Antipro-Liferative Activities 2015
102 Lipases-catalyzed enantioselective kinetic resolution of alcohols 2015
103 Optogenetic Inhibitor of the Transcription Factor CREB 2015
104 Cu (I) Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition (CuAAC): Synthesis of 17α-[1-(Substituted Phenyl)-1,2,3-Triazol-4-yl]-19-Nortestosterone-17β-yl Acetates Targeting Progestational and Antipro-Liferative Activities 2015
105 Synthesis and In Vitro Evaluation of Ferutinol Aryl Esters for Estrogenic Activity and Affinity Toward Cannabinoid Receptors 2015
106 Optimizing the Photocontrol of bZIP Coiled Coils with Azobenzene Crosslinkers: Role of the Crosslinking Site 2015
107 Lipases-catalyzed enantioselective kinetic resolution of alcohols 2015
108 Synthesis, Biological Investigation and Molecular Docking Study of N-Malonyl-1,2-dihydroisoquinoline Derivatives as Brain Specific and Shelf-Stable MAO Inhibitors 2015
109 Photo-Control of DNA Binding by an Engrailed Homeodomain–Photoactive Yellow Protein Hybrid 2015
110 Phenothiazine-Derived Antipsychotic Drugs Inhibit Dynamin and Clathrin-Mediated Endocytosis 2015