Department Researches & Publications

Faculty of Pharmacy

Assiut University

Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
131 "Design and Synthesis of Novel P450 Inhibitors for the Treatment of Tuberculosis", 2nd international conference and exhibition " 2013
132 "Design and Synthesis of Novel P450 Inhibitors for the Treatment of Tuberculosis", 2nd international conference and exhibition " 2013
133 Novel Schiff Bases of Indoline-2,3-Dione and Nalidixic Acid Hydrazide: Synthesis, In Vitro Antimycobacterial and In Silico Mycobacterium Tuberculosis (Mtb) DNA Gyrase Inhibitory Activity 2012
134 Design and Synthesis of 17α-(1-Substituted-1,2,3–Triazol-4-yl)-19-Nortestosterone Acetate Derivatives Using Click Chemistry.
 		2012
135 Design and Synthesis of 17α-(1-Substituted-1,2,3–Triazol-4-yl)-19-Nortestosterone Acetate Derivatives Using Click Chemistry.
 		2012
136 Synthesis and Anti-Inflammatory Activity of Some Pyrazole Derivatives 2012
137 NGR peptide ligands for targeting CD13/APN identified through peptide array screening resemble fibronectin sequences 2012
138 Design, Synthesis and Pharmacophoric Model Building of Novel Substituted Nicotinic Acid Hydrazones with Potential Antiproliferative Activity 2012
139 Design and Synthesis of 17α-(1-Substituted-1,2,3–Triazol-4-yl)-19-Nortestosterone Acetate Derivatives Using Click Chemistry.
 		2012
140 Novel amino acid derivatives of naproxen for colon cancer chemoprevention. 2012