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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
331 Antigiardial Activity of Metronidazole Twin Ester Prodrugs. 2001
332 In vitro and in-vivo evaluation of an amylobarbitone/hydroxypropyl-β-cyclodextrin complex prepared by a freeze-drying method. 2000
333 Investigation of Alkylating, Antineoplastic and Anti-HIV Potentials of the Chalcones; 2-(3-Arylpropenoyl)benzimidazole and Their Corresponding N1-Methyl Derivatives. 2000
334 Effective and Variable Functionalization of Pyrazolo[1,5-a]pyridines Involving Palladium-Catalyzed Coupling Reactions. 2000
335 Cyclic amide derivatives as potential prodrugs: N-hydroxymethyl-succinimide-/isatin esters of some NSAIDs as chemical delivery system with improved therapeutic index. 1999
336 Cyclic amide derivatives as potential prodrugs: N-hydroxymethyl-succinimide-/isatin esters of some NSAIDs as chemical delivery system with improved therapeutic index. 1999
337 Cyclic amide derivatives as potential prodrugs: N-hydroxymethyl-succinimide-/isatin esters of some NSAIDs as chemical delivery system with improved therapeutic index. 1999
338 Anticonvulsant Activity of Paeonimetabolin-I Adducts Obtained by Incubation of Paeoniflorin and Thiol Compounds with Lactobacillus brevis. 1999
339 Anticonvulsant Activity of Paeonimetabolin-I Adducts Obtained by Incubation of Paeoniflorin and Thiol Compounds with Lactobacillus brevis. 1999
340 Anticonvulsant Activity of Paeonimetabolin-I Adducts Obtained by Incubation of Paeoniflorin and Thiol Compounds with Lactobacillus brevis. 1999