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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
361 Chitosan Conjugates of Ibuprofen and Flurbiprofen: Synthesis, Characterization and in vitro Stability. 1998
362 Potent Anticonvulsant Paeonimetabolin-I Derivatives Obtained by Incubation of Paeoniflorin and Sulfhydryl Compounds With Lactobacillus Brevis. 1998
363 Esters Twin Drugs of Metronidazole : Synthesis, Physicochemical properties, Kinetic studies and Antigardial activity. 1998
364 Flow injection analysis of amino acids using Cu(II) oxide as a packed reactor for ultraviolet detection. 1998
365 Metronidazole Twin Ester Prodrugs II : Non Identical Twin Esters of Metronidazole and Some Antiprotozoal Halogenated Hydroxyquinoline Derivatives. 1998
366 Potent Anticonvulsant Paeonimetabolin-I Derivatives Obtained by Incubation of Paeoniflorin and Sulfhydryl Compounds With Lactobacillus Brevis. 1998
367 Esters Twin Drugs of Metronidazole : Synthesis, Physicochemical properties, Kinetic studies and Antigardial activity. 1998
368 Cyclic amide derivatives as potential prodrugs: N-hydroxmethyl-succinimide-/isatin esters of some NSAIDs as chemical delivery system with improved therapeutic index. 1998
369 Metronidazole Twin Ester Prodrugs II : Non Identical Twin Esters of Metronidazole and Some Antiprotozoal Halogenated Hydroxyquinoline Derivatives. 1998
370 Polymeric prodrug:  and -poly (N-hydroxy-ethyl) aspartamide as carrier for controlling the release of theophylline. 1998