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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
401 Design and synthesis of some new 1H-1,2,4-triazoles of potential anti inflammatory and analgesic activities 1994
402 Synthesis, Hydrolysis Kinetics, Lipophilicity, and Biological Activity of N4-(3-Alkoxy and Benzyloxycarbonylpropionyl)-Ara-C Prodrugs. 1993
403 Heptakis (2,6-di-O-methyl)-β-cyclodextrin complexation with glutethimide, 1993
404 1HNMR and chelating properties of 1,5-dimethyl-N-substituted-1H-pyrazole-3- carboxamides and 1,3-dimethyl-N-substituted-1H-pyrazole-5-carboxamides. 1993
405 1HNMR and chelating properties of 1,5-dimethyl-N-substituted-1H-pyrazole-3- carboxamides and 1,3-dimethyl-N-substituted-1H-pyrazole-5-carboxamides. 1993
406 Synthesis and preliminary alkylating activites of certain new 1,4 dihydropyridine, pyridinium salts and 2,7-diazabicyclo(4,1,10)hept-3-enes 1993
407 Synthesis and preliminary alkylating activites of certain new 1,4 dihydropyridine, pyridinium salts and 2,7-diazabicyclo(4,1,10)hept-3-enes 1993
408 Synthesis, Hydrolysis Kinetics, Lipophilicity, and Biological Activity of N4-(3-Alkoxy and Benzyloxycarbonylpropionyl)-Ara-C Prodrugs. 1993
409 Synthesis and preliminary alkylating activites of certain new 1,4 dihydropyridine, pyridinium salts and 2,7-diazabicyclo(4,1,10)hept-3-enes 1993
410 Synthesis, Hydrolysis Kinetics, Lipophilicity, and Biological Activity of N4-(3-Alkoxy and Benzyloxycarbonylpropionyl)-Ara-C Prodrugs. 1993