Iron-Mediated Cleavage of C-C Bonds in Vicinal Tricarbonyl Compounds in Water

Faculty of Pharmacy

Assiut University

Iron-Mediated Cleavage of C-C Bonds in Vicinal Tricarbonyl Compounds in Water

Research Authors
Jasmin Mecinović, Refaat B. Hamed, Christopher J. Schofield
Research Department
Department of Pharmacognosy
Research Journal
Angew. Chem. Int. Ed., DOI: 10.1002/anie.200806296
Research Rank
1
Research Vol
Vol. 48
Research Year
2009
Research Member
Refaat Hamed
Research Abstract

Three of a kind: Vicinal tricarbonyl compounds undergo C-C cleavage mediated by ferric ions (see scheme). The observed cleavage of ninhydrin and dehydroascorbic acid has relevance for amino acid detection and the metabolism of vitamin C.