Photoactivable Peptides for Identifying Enzyme–Substrate and Protein–Protein Interactions

Faculty of Pharmacy

Assiut University

Photoactivable Peptides for Identifying Enzyme–Substrate and Protein–Protein Interactions

Research Authors
Dante Rotili, Mikael Altun, Refaat B. Hamed, Christoph Loenarz, Armin Thalhammer, Richard J. Hopkinson, Ya-Min Tian, Peter J. Ratcliffe, Antonello Mai, Benedikt M. Kessler, Christopher J. Schofield
Research Department
Department of Pharmacognosy
Research Journal
Chem. Commun,doi: 10.1039 /c0cc04457a
Research Rank
1
Research Vol
Vol. 47, No. 5
Research Year
2011
Research Member
Refaat Hamed
Research Abstract

Photoactivated cross-linking of peptides to proteins is a useful strategy for identifying enzyme–substrate and protein–protein interactions in cell lysates as demonstrated by studies on the human hypoxia inducible factor system.