Microwave-Assisted One-Step Synthesis of Fenamic Acid Hydrazides from the Corresponding Acids

Faculty of Pharmacy

Assiut University

Microwave-Assisted One-Step Synthesis of Fenamic Acid Hydrazides from the Corresponding Acids

Research Authors
Tarek Aboul-Fadl, Hatem A. Abdel-Aziz, Adnan Kadi, Ahmed Bari, Pervez Ahmad, Tilal Al-Samani, Seik Weng Ng
Research Department
Department of Medicinal Chemistry
Research Journal
Molecules, doi: 10.3390/molecules16053544
Research Rank
1
Research Vol
Vol.  16
Research Website
http://www.mdpi.com/1420-3049/16/5/3544/
Research Year
2011
Research Member
Tarek Aboul-Fadl Mohammad Hassan
Research Abstract

A facile and efficient method for synthesis of fenamic acid hydrazides from their acids in one-step reaction under microwave irradiation and solvent-free conditions was developed. Compared with the two-step conventional heating method, the process was simple, the reaction time was very short and the yields were almost quantitative.