Naturally occurring didemnaketals, structural elucidation, features, and pharmacological activities.

Faculty of Pharmacy

Assiut University

Naturally occurring didemnaketals, structural elucidation, features, and pharmacological activities.

Research Authors
Gamal A Mohamed, Sabrin RM Ibrahim, Diaa TA Youssef
Research Department
Department of Pharmacognosy
Research Journal
Bull. Facu. Pharm., Cairo University (B-FOPCU)
Research Publisher
Elsevier
Research Rank
1
Research Vol
53
Research Website
http://dx.doi.org/10.1016/j.bfopcu.2015.02.003
Research Year
2015
Research Member
Sabrin Ragab Mohamed Ibrahim
Research Abstract

Didemnaketals are rare terpenoid class reported only in the marine ascidian Didemnum species. They possess important biological activities like HIV-1 protease inhibitor, protein kinase inhibition, antimicrobial, antiproliferative, and cytotoxic. A compilation of new naturally occurring didemnaketals reported during 1991–2014 is provided with available physical and spectral data: mp,[a]D, UV, IR, 1H and 13C NMR as well as biological activities and references.