The chemical composition, antimicrobial, anti-inflammatory, antioxidant and cytotoxic
activities of the extracted essential oils (EOs) of capetula and shoots of Senecio glaucus L. were determined. The main constituents are m-mentha-1(7),8-diene (31.4 % and 25.6 % of total capetula and shoot oils, respectively), cis-m-mentha-2,8-diene (22.9 % and 8.2 %), dehydrofukinone (17.2 % and 19.9 %), α-terpinolene (3.9 % and 3.1 %) and 2,5-cyclohexadiene-1,4-dione,2-(1,1- dimethylethyl)-5-(2-methyl-2-propen-1-yl)- (3.9 % and 3.4 %). Sabinene constitutes about 2.7 % of the capetula EO, but not detected in shoot oil. α-Fenchene and 1,3,8-p-menthatriene represented by 5.6 % and 5.3 % respectively, in the shoot EO, but not detected in capetula oil. More than half of the oils was monoterpenes, followed by sesquiterpenes. Both EOs differentially exerted antimicrobial effects on Gram-positive and Gram-negative bacteria, yeasts and molds. Capetula oil showed anti-inflammation effect higher than the shoots oil. The EOs showed strong antioxidant effect with EC50 values for scavenging DPPH radical of 1.6 and 1.9 μl/ ml for capetula and shoot EOs, respectively, compared to 16 μg/ ml for ascorbic acid. So, the capetula EO was more potent against human breast cancer cells than shoots EO.
Research Department
Research Journal
Journal of Essential Oil Bearing Plants
Research Publisher
Taylor & Francis
Research Rank
1
Research Vol
23(1)
Research Website
https://www.tandfonline.com/doi/abs/10.1080/0972060X.2020.1742797
Research Year
2020
Research Member
Research Abstract