Synthesis and Antiviral Activity of Novel [1,2,4]triazolo[3,4-b][1,3,4] Thiadiazoles, [1,2,4]triazolo[3,4-b] [1,3,4]Thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4]Thiadiazipenes

Faculty Of Science

Assiut University

Synthesis and Antiviral Activity of Novel [1,2,4]triazolo[3,4-b][1,3,4] Thiadiazoles, [1,2,4]triazolo[3,4-b] [1,3,4]Thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4]Thiadiazipenes

Research Authors
Abdel-Rahman Farghaly, Erik De Clerq and Hussein El-Kashef
Research Abstract

Starting from the 4-amino-3-(1,3-diphenyl-1H-pyrazol-4-yl)-4,5-dihydro-[1,2,4] triazole-5(1H)-
thione 2, a series of new [1,3,4]thiadiazoles 3, 4, 7 and [1,3,4] thiadiazines 8, 10, 11, 12, 14 were
prepared. Also, [1,3,4]thiadiazepines 16-18 could be synthesized. Some of the newly prepared
compounds were evaluated for their antiviral potential.

Research Department
Department of chemistry
Research Journal
Arkivoc (X)
Research Member
Hussein Mohamed salama El-kashef
Research Rank
1
Research Year
2006
Research Pages
pp. 137-151